Circulatory System Pregnancy and Childbirth Cardiology
Conditions
Interventions
oral administration of labetalol
Oral administration of Nifedipine
Sponsors
self
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women who delivered after 28 weeks of gestation irrespective of route of delivery and their blood pressures postpartum were =150/100mmHg. All women who give their consent to participate in the research
Exclusion criteria
Exclusion criteria: 1. Women with known allergy to either nifedipine or labetalol 2. Sickle cell disease patients 3. Hypertensive women with previous/family history of depression or psychiatric illness 4. Women with hypertensive emergency (defined as BP = 180/120 mmHg). 5. Known asthmatic patients 6. Women with other co-morbidities like diabetes mellitus, renal failure, heart failure, heart block etc in the pregnancy 7. Women with morbid obesity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the average time interval taken to achieve blood pressure control sustained for 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the potential need for dose escalation when using long-acting oral nifedipine versus oral labetalol for hypertension management in postnatal women in Enugu. To determine and compare the proportion of participants with the need for additional antihypertensive agents between the use of long-acting oral nifedipine and oral labetalol in control of hypertension in postnatal women in Enugu. To determine and compare patient reported side effects recorded following the use of long-acting oral nifedipine or oral labetalol in control of hypertension in postnatal women in Enugu | — |
Countries
Nigeria
Contacts
Public ContactIfeanyi Johnson Onyekpa
Consultant ESUTH Parklane GRA Enugu
Outcome results
None listed