Pregnancy and Childbirth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All consenting women for elective lower segment caesarean delivery under spinal anaesthesia after 37weeks gestational age.
Exclusion criteria
Exclusion criteria: Medical conditions in pregnancy (Hypertension, Diabetes mellitus and known asthmatics) Pregnant women with history of previous uterine surgeries (Caesarean sections, myomectomy etc.) Preoperative anaemia (packed cell volume less than 30% twenty four hours prior to surgery). Pregnant women with history of coagulation disorders Pregnant women with twin gestation Pregnancy co-existing with uterine fibroids Febrile illness before surgery Pregnant women who have contraindication to misoprostol use examples allergy and asthmatics. Cases of Emergency caesarean section and ruptured uterus Cases of APH – Placenta Praevia and Abruptio Placentae.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean intra-operative blood loss during caesarean delivery and change in haematocrit 48 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measures will include the proportion of participants that will need additional uterotonics, and those who received intraoperative blood transfusion, and the need for other surgical intervention for PPH (such as B-lynch procedure, or hysterectomy), incidence of postpartum maternal anaemia and occurrence of adverse effects (nausea, vomiting, allergic reaction, pyrexia, etc.) | — |
Countries
Nigeria
Contacts
Lecturer 1