Respiratory
Conditions
Interventions
Synchronized Intermittent Mandatory Ventilation in Acute Exacerbations of Chronic Obstructive Pulmon
Pressure Regulated Volume Control Ventilation in patients with Chronic Obstructive Pulmonary Disease
Sponsors
Al Azhar University hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: COPD patients respiratory arrest hypotensive shock uncontrolled cardiac ischemia inability to protect the airway excessive secretions agitation or uncooperativeness conditions that preclude the placement of a mask or the achievement of a proper fit Severe acidosis (pH 60 mmHg) Life-threatening hypoxemia Tachypnea >35 breaths/min Impaired mental status
Exclusion criteria
Exclusion criteria: COPD patients with Acute respiratory distress syndrome Acute myocardial infarction Chronic renal failure Decompensated liver cell failure Massive pulmonary embolism Pneumothorax Massive pleural effusion patients who were successfully extubated within the first 24 hours of ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| measuring the Improvement in Oxygenation (PaO2/FiO2 Ratio), Ventilation Efficiency (PaCO2 Levels & pH), Duration of Mechanical Ventilation, Weaning Success Rate. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Ventilator-Associated Pneumonia, Long-Term Outcomes, Hemodynamic Stability, Patient Comfort & Synchrony, Barotrauma, and Lung Injury, ICU Length of Stay and ICU ventilator-free days, Reintubation Rate, Hospital Mortality. | — |
Countries
Egypt
Contacts
Public ContactWageeh Sayed
lecturer of Chest Disesea AlAzhar University Assiut
Outcome results
None listed