Pregnancy and Childbirth Postpartum infections
Conditions
Interventions
Azithromycin
Sponsors
Igodo Udien Sarah
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: All women who give consent and had hospital-supervised vaginal delivery at term without added risk for infection.
Exclusion criteria
Exclusion criteria: 1. Intrapartum fever =38°C or maternal sepsis 2. Penicillin or Macrolide allergy 3. History of anaphylaxis (a severe hypersensitivity reaction) to Penicillins or Macrolides, as documented in hospital notes. 4. Exposure to any antibiotic agent within 1 week before delivery 5. Prolonged rupture of membranes (=24 hrs) 6. Prolonged labour(>12hrs) 7. Suspected chorioamnionitis 8. Intrauterine fetal death 9. Women who do not give consent 10. Women who had home delivery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical endometritis defined as when at least two of the following signs or symptoms are present: fever (=38°C), abdominal pain, uterine tenderness, or purulent drainage from the uterus, delay in uterine involution (less than 2cm per day during the first 8 days after delivery) with no other recognized cause and perineal wound infection. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital readmission for presumed maternal infection within 42days of delivery, use of additional maternal antibiotic therapy. | — |
Countries
Nigeria
Contacts
Public ContactWaripamo Petre Oweisi
Consultant Obgyn
Outcome results
None listed