Efficacy of intraoperative Dexmedetomidine infusion for mitigating emergence agitation in elderly patients undergoing abdominal cancer surgery. A prospective controlled trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202502657476266

Enrollment

Registered

2025-02-10

Start date

2025-01-15

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental and Behavioural Disorders

Interventions

dexmedetomidine infusion

normal saline infusion

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA) grade I , II and III. • Both gender; male and female (more than 60 years old). • Elective abdominal cancer surgery (rectum, colon, stomach, esophagus). • surgery must be more than 2 hours.

Exclusion criteria

Exclusion criteria: ASA) grade IV. • Sever cardiac disease (coronary, valvular, hypertensive). • Difficult airway patients (such as Mallampati airway classification III, airway malformation • Chronic pain medications • History of mental illness or long-term psychotropic drug usage • Patients taking anticonvulsant and antidepressant drugs. • neuromuscular disease

Design outcomes

Primary

Measure	Time frame
During emergence, the level of agitation will be evaluated using the Ricker sedation-agitation scale	—

Secondary

Measure	Time frame
Grade of cough during emergence was assessed using a four-point scale (0 no cough; 1 single cough; 2 persistent cough lasting 5 s and 3 persistent cough lasting =5 s or bucking).	—

Countries

Egypt

Contacts

Public Contactsalma ahmed

lecturer of anesthesia and icu

salmaelsayed84@mans.edu.eg00201002990553

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026