Human papillomavirus
Conditions
Interventions
National Immunization Program Vaccinated Cohort
First void urine self sample National immunization Program cohort age matched unvaccinated
First void urine self sample Pilot Vaccinated Cohort
First void urine self sample Pilot Program cohort age matched unvaccinated
Sponsors
University of Antwerp
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria for the Gavi pilot cohort • Females aged 18 – 30 years who were included in the pilot vaccination of the Gavi demonstration program cohort • Willing to give informed consent to the research team and fill out a short survey Inclusion criteria for the National Immunization Program (NIP) cohort • Young adolescents and adults (targeted by the NIP) • Willing to give informed consent to the research team, obtain parental consent, and fill out a short survey
Exclusion criteria
Exclusion criteria: • Pregnancy – performance of antibody detection in the urine sample of pregnant women has not been studied • Immunocompromised women due to lower immune response
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HPV DNA status in first-void urine samples of HPV vaccinated and vaccinated cohorts. ;Concentration of total and HPV-specific IgG (immunoglobulin G) in first-void urine.;Level of knowledge and training gaps on HPV vaccination among healthcare workers. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate the feasibility of first-void urine sampling for HPV vaccination status in various settings | — |
Countries
Kenya, Senegal, Uganda
Contacts
Public ContactDur E Nayab Waheed
Senior Researcher
Outcome results
None listed