Circulatory System Surgery uterine fibroid
Conditions
Interventions
Group 1 intravenous tranexamic acid group
GROUP II sublingual misoprostol group
Sponsors
Esan Babatunde Ayodeji
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Women with uterine fibroid who agree to participate in this study and schedule for primary abdominal myomectomy
Exclusion criteria
Exclusion criteria: (1) Women with previous uterine surgery (previous myomectomy, caesarean delivery). (2) Pregnant women. (3) Women who have allergy or hypersensitivity to Tranexamic acid. (4) Women with severe endometriosis, malignancy or chronic medical disorders like hypertension, cardiac and pulmonary diseases, chronic endocrine or metabolic diseases such as diabetes, obesity (body mass index >30kg/m2). (6) Patients with bleeding disorder (7) Patient who refused to partake in the study (8) Patient who has received preoperative hormonal therapy (such as GnRH analogue or oral contraceptives pills) that could affect the intra operative bleeding and the duration of operation. (9) Patients for laparoscopic or hysteroscopic myomectomy (10) Women who had contraindications or allergy to misoprostol based on questions including the experience of skin eruptions, urticaria, rash, shortness of breath, cough, chest pain in prior misoprostol administrations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimation of total blood loss at surgery;Estimation of total blood loss at surgery- Visual and gravimetric method of estimating blood loss will be used to estimate the blood loss during the surgery. An electronic weighing machine that could weigh between 0.1g to 500g will be used to measure the baseline weight of the dry abdominal packs and gauze. The weight of the blood soaked abdominal pack and gauzes will be measured with an electronic weighing machine after the surgery. The difference between the weight of the dry abdominal pack and gauze from the weight of the soaked abdominal pack and gauze in gram is equivalent to the weight of the blood loss in gram. I gram difference in the weight is equal to I milliliter of blood. The total blood loss will be calculated by adding the volume of blood in the calibrated measuring jar and on the operating drapes with the equivalent milliliter of the weighed materials gotten from the gravimetric method. ;Estimation of total blood loss at surgery;estimation of total blood loss intraoperativel | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time in minute from skin incision to skin closure, operation time in minute starting from first uterine incision to closure of last uterine incision, postoperative stay in hospital in days and the need for blood transfusion either intraoperatively or postoperatively. ;Operation time in minute from skin incision to skin closure, operation time in minute starting from first uterine incision to closure of last uterine incision, postoperative stay in hospital in days and the need for blood transfusion either intraoperatively or postoperatively;Operation time in minute from skin incision to skin closure, operation time in minute starting from first uterine incision to closure of last uterine incision, postoperative stay in hospital in days and the need for blood transfusion either intraoperatively or postoperatively.;1. operation time in minute from skin incision to skin closure. 2. , operation time in minute starting from first uterine incision to closure of last uterine incision. 3.postoperative stay in hospital in days and the need for blood transfusion either intraoperatively or postoperatively | — |
Countries
Nigeria
Contacts
Public Contactjoyce esan
nursing lecturer
Outcome results
None listed