Surveillance of Neonatal Sepsis and analysis of preterm gut microbiome at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania

Microbial Surveillance and Gut Microbiomics in Neonatal Sepsis, Tanzania (MS-GM-NST) study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202502518189291

Enrollment

2000

Registered

2025-02-20

Start date

2023-10-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal Diseases Paediatrics

Interventions

just observational no intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Preterm infants 28+0 to <34 weeks of gestational age - Within the age of 28 days of life - Minimum birth weight of 1000 g

Exclusion criteria

Exclusion criteria: - Extreme preterm babies born before 28 weeks GA or less than 1000g. - Mothers below 18 years of age - Babies admitted who are above 28 days of life - Unwillingness of the parent or guardian to participate in the study. - Clinical use of probiotics in the mother or infant. - Severe comorbidities in the infant like birth asphyxia, and severe congenital malformations incompatible with life, and genetic metabolic diseases. - Severe co-morbidities or death of the mother making her unable to visit, or provide care for her infant throughout the hospital stay.

Design outcomes

Primary

Measure	Time frame
Incidence of blood-culture proven sepsis among preterm infants;Presence of dysbiosis of the gut microbiome	—

Secondary

Measure	Time frame
clinical suspected sepsis, death from any cause;colonization with multiresistent bacteria until day 28 of life in a subgroup of preterms	—

Countries

Tanzania

Contacts

Public ContactFatima Mussa

Study Coordinator

f_mussa@icloud.com+255688239200

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026