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The effect of PRP on healing of traumatic tympanic membrane perforation

The effect of using Platelet Rich Plasma on healing of traumatic tympanic membrane perforation versus spontaneous healing: A comparative study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202501804212116
Enrollment
40
Registered
2025-01-17
Start date
2024-10-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ear, Nose and Throat

Interventions

Platlet rich plasma group
Conservative healing group

Sponsors

faculty of medicine Alazhar university hospital assiut
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Inactive middle ear cleft disease ( No active discharge ). - Pure Tone Audiogram with conductive hearing loss, Air-bone gap (ABG) =30 dB, and normal middle ear pressure - Patients with No history of coagulopathies and no use of anticoagulants within the previous 10 days. - Traumatic perforation within the previous 7 days

Exclusion criteria

Exclusion criteria: - History of Previous Otological Surgery. - History of hearing loss before trauma. - Traumatic perforation of more than 7 days. - Traumatic perforation with active discharge or recent infection at the time of presentation. - Pure Tone Audiogram with Sensorineural hearing loss or conductive hearing loss with Air bone gap > 30 dB or abnormal middle ear pressure. - Patients with a history of coagulopathies or taking anticoagulants within the previous 10 days. - Patients with URTI ( Rhinitis, Sinusitis, Tonsillopharyngitis )

Design outcomes

Primary

MeasureTime frame
Correction of the Mean Air Bone gap;recovery rate ;Duration of healing

Secondary

MeasureTime frame
improvement of associated symptoms vertigo ,otalgia , dizziness

Countries

Egypt

Contacts

Public ContactMohammed Atef

Lecturer of otorhinolarnyngology Faculty of medicine alazahr university hospital

Purelove11285@gmail.com0201091856193

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026