Comparing Paracetamol-Diclofenac and Pentazocine-Diclofenac Combinations for Post-Caesarean Pain Relief

Post Caesarean Analgesia: Towards an Opioid-Sparing Drug Selection

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202501703002153

Enrollment

318

Registered

2025-01-27

Start date

2021-11-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

Paracetamol plus diclofenac

Diclofenac plus pentazocine

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 18 years old and above undergoing Elective or emergency Caesarean section Under regional anaesthesia.

Exclusion criteria

Exclusion criteria: Peptic ulcer disease Severe Pre-eclampsia Renal and hepatic insufficiency History of pre-existing opioid dependence Allergic reaction to pentazocine, paracetamol or diclofenac Bleeding diathesis Intrauterine foetal death Patients who had Caesarean delivery under general anaesthesia Patients who developed intraoperative complication such as PPH

Design outcomes

Primary

Measure	Time frame
Assessment of postoperative pain levels using the Visual Analogue Scale (VAS)	—

Secondary

Measure	Time frame
Patient satisfaction with postoperative pain management at the 24th postoperative hour.	—

Countries

Nigeria

Contacts

Public ContactAyokunle Olumodeji

Consultant Lagos State University Teaching Hospital

ayokunleolumodeji@yahoo.com2348032751080

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026