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Efficacy of Adding Hyaluronidase to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia after Abdominal Hysterectomy

Efficacy of Adding Hyaluronidase to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia after Abdominal Hysterectomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202501501517422
Enrollment
50
Registered
2025-01-23
Start date
2024-12-21
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Bupivacaine alone group
Bupivacaine and Hyaluronidase group

Sponsors

Al Azhar university
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: adult female patients scheduled for elective total abdominal hysterectomy American Society of Anesthesiologists (ASA) class I or II

Exclusion criteria

Exclusion criteria: hysterectomy for emergency indications bleeding disorders or on anticoagulants severe respiratory and cardiovascular diseases history of allergy to local anesthetics

Design outcomes

Primary

MeasureTime frame
postoperative VAS score

Secondary

MeasureTime frame
the total dose of nalbuphine consumption

Countries

Egypt

Contacts

Public ContactMohammed Abu hatab

associate professor of Anesthesia and Intensive Care

drm_star2000@yahoo.com00201003127342

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026