Dry eye after refractive surgery

Evaluation of Tear Meniscus Using Anterior Segment Optical Coherence Tomography after Corneal Photorefractive Surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202412884669257

Enrollment

Registered

2024-12-12

Start date

2023-12-25

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

conventional microkeratome LASIK

PRK refractive correction

FS SMILE refractive correction

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Myopic patients aged = 21 years with a spherical equivalent range between -1.50 to - 8.00 diopters and cylinders less than -2.00 diopters with stable refractive errors for at least one year. Patients should have pre-operative normal corneal topography.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of previous ocular surgery 2) Patients with ocular surface disease, contact lens wear, ocular medications that affect tear secretion, or tear replacement therapy. 3) Patients with corneal dystrophy, keratoconus, or corneal scarring. 4) Posterior segment pathology (i.e. diabetic retinopathy, glaucoma, etc.) 5) Patients with a history of systemic autoimmune disease.

Design outcomes

Primary

Measure	Time frame
To evaluate changes in tear meniscus measurement using AS-OCT evaluation after the three corneal refractive procedures; LASIK, PRK, and FS-SMILE	—

Secondary

Measure	Time frame
To report any complications related to the three refractive procedures	—

Countries

Egypt

Contacts

Public ContactAli Goda Ali

Lecturer of ophthalmology

AGMohammed@medicine.zu.edu.eg+0201149880064

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026