Digestive System Helicobacter pylori
Conditions
Interventions
Conventional first line H. pylori treatment
Treatment with Levofloxacin based triple regimen
Sponsors
Dr. Igbiti Justice
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who presented to the General Out-patient Clinic (GOPC) and the Medical Out-patient Clinic (MOPC) with dyspepsia as defined by chronic or recurrent epigastric discomfort or pain with or without bothersome post-prandial fullness and early satiety, who tested positive for H. pylori using the SAT. 2. Patients who were at least 18 years old
Exclusion criteria
Exclusion criteria: 1. Patients with ‘alarm’ features. 2. Patients who had first-line treatment for H. pylori within the preceding 4 weeks. 3. Patients who were pregnant. 4. Patients with documented allergies to any of the drugs being compared in the study 5. Patients with documented background end-stage kidney disease 6. Patients with established chronic liver disease 7. Patients who have been on PPIs or H2-receptor antagonists for at least two weeks prior to recruitment 8. Patients who had been on antibiotics or Bismuth-containing agents for at least four weeks before recruitment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of eradication rates in both groups | — |
Countries
Nigeria
Contacts
Public ContactJustice Igbiti
Senior Registrar
Outcome results
None listed