Skip to content

Opioid free anesthesia versus opioid based anesthesia in laparoscopic hysterectomy

Opioid-free anesthesia versus opioid-based anesthesia in patients undergoing laparoscopic hysterectomy: A prospective randomized double blind controlled study.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202412807769214
Enrollment
68
Registered
2024-12-02
Start date
2024-08-15
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Opoid based anesthesia

Sponsors

Mansoura University Hospitals
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women aged between 40 to 70 years American Society of Anesthesiologists physical status (ASA) I & II undergoing scheduled laparoscopic hysterectomy

Exclusion criteria

Exclusion criteria: patients refusal, body mass index >35 kg m- 2, hepatic, renal and cardiac insufficiency, DM history of chronic pain, psychiatric disease, allergy, contraindication to any of the study drugs, inability to assess pain.

Design outcomes

Primary

MeasureTime frame
The main result of this research (primary outcome) will be the visual analogue scale (VAS) on the first postoperative day in the PACU and ward, including the highest VAS pain levels within the 2, 6, 12, 24 and 48 h following surgery.

Secondary

MeasureTime frame
The secondary outcome indicators for this study include the total amount of fentanyl, dexmedetomidine, and propofol used during the procedure, as well as hemodynamic data such as the profile of MAP, HR, and SpO2 at various measurement times (before induction, after induction, immediately after tracheal intubation, after artificial pneumoperitoneum, at cessation of anesthetics and immediately after extubation). Additionally, postoperative opioid-related adverse events will be recorded.

Countries

Egypt

Contacts

Public ContactMohamed Albayomy

Resident

Mohamed.awad.1294@gmail.com0201005409807

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026