Different Intravenous Regimens for Prevention of Post Dural Puncture Headache after Spinal Anesthesia for Elective Caesarean Section

Comparison between Different Intravenous Regimens for Prevention of Post Dural Puncture Headache after Spinal Anesthesia for Elective Caesarean Section

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202412781041756

Enrollment

100

Registered

2024-12-17

Start date

2024-12-29

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Neostigmine group

Aminophylline group

Synacthen group

Control group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: elective cesarian section belonging to the American Society of Anesthesiologists (ASA) I, II physical status body mass index (BMI) < 30 kg/m2, height from 160 to 170 cm

Exclusion criteria

Exclusion criteria: emergency cesarean section history of migraine, chronic headache, or previous PDPH history of analgesic consumption, substance abuse, and smoking chronic or gestational hypertension hypersensitivity to one of the used drugs cardiovascular diseases, respiratory system diseases, neurological and psychiatric disorders massive blood loss and intraoperative nausea and vomiting

Design outcomes

Primary

Measure	Time frame
incidence of Post Dural Puncture Headache after Spinal Anesthesia	—

Secondary

Measure	Time frame
the severity of Post Dural Puncture Headache after Spinal Anesthesia	—

Countries

Egypt

Contacts

Public Contactmahmoud Ahmed

lecturer of Anesthesia and Intensive Care

dreamobeng@gmai.com00201002005052

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026