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intrathecal dexmedetomidine or morphine as Adjuvant to Bupivacaine for normal Labour Analgesia.

Safety and Efficacy of intrathecal dexmedetomidine or morphine as Adjuvant to Bupivacaine for normal Labour Analgesia. A Randomized Clinical Study.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
PACTR
Registry ID
PACTR202412669162158
Enrollment
90
Registered
2024-12-31
Start date
2023-11-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Dexmedetomidine Group

Sponsors

Al Azhar University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Multiparous women, 21–40 years old. Pregnant woman who received antenatal care. Pregnant woman presented for vaginal delivery of uncomplicated term pregnancy of singleton foetus. Pregnant woman with engaged foetal head and cervical dilatation of at least 4-6 cm requiring oxytocin augmentation, and requested analgesia

Exclusion criteria

Exclusion criteria: Patients with pre-existing or pregnancy-induced hypertension. Abnormal foetal heart rate (FHR) tracings. Obesity, endocrinal diseases and/or diagnosed foetal abnormalities. Contraindication to neuraxial block. Allergy to any of the study drugs and need for intrapartum antiemetic or antispasmodic drugs. Parturient who was at high risk for cesarean section. Refused to participate was excluded.

Design outcomes

Primary

MeasureTime frame
To assess the efficacy of intrathecal dexmedetomidine and morphine in reducing pain during and after delivery which assessed by Change on the visual analog scale (VAS) for pain (0 =no pain to 10 = the maximum pain) to assessment the duration of analgesia during and after delivery.

Secondary

MeasureTime frame
The secondary aim will be to study the complication and adverse effect on the mother and fetus.

Countries

Egypt

Contacts

Public ContactMedhat Fathi

Lecturer of Obstetrics and Gynecology

medhat3027@yahoo.com00201093944921

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026