A controlled randomized clinical trial of the efficacy and safety of hyaluronidase as an adjuvant to bupivacaine in ultrasound-guided supraclavicular brachial plexus block

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202412466230537

Enrollment

Registered

2024-12-31

Start date

2022-03-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Group I

Group II

Group III

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 19 - 44 years American Society of Anesthesiologists (ASA) physical status grades I, and II. Patients scheduled for elective surgery of the upper limb.

Exclusion criteria

Exclusion criteria: Patients who refused or had neurological affection of the upper limb, bleeding diathesis, mental illness, history of drug addiction, chronic analgesic use, or history of local anesthetic allergy were excluded from the study.

Design outcomes

Primary

Measure	Time frame
Duration of sensory block and pain relief as assessed by visual analog scale (VAS).	—

Secondary

Measure	Time frame
The onset of sensory and motor blocks and time to first rescue analgesia;hemodynamic parameters (heart rate, mean arterial pressure, and oxygen saturation) and postoperative complications (Horner’s syndrome, voice changes, and pneumothorax).	—

Countries

Egypt

Contacts

Public ContactMohamed Barakat

Doctor of Anaesthesiology

mohamedbarakat27291@gmail.com+201022358484

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026