Comparing between Sodium Bicarbonate, Magnesium Sulphate and Hyaluronidase as additives to Peribulbar Anesthesia in Vitreoretinal Surgeries: A Randomized Double Blind Comparative Study

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202411773240995

Enrollment

Registered

2024-11-11

Start date

2024-04-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Hyaluronidase Group

Sodium Bicarbonate Group

Magnesium Sulphate Group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult of both sexes Age 18 to 70 years American Society of Anesthesiologists physical status I and II Patients with previous complications Patients refusing general anesthesia

Exclusion criteria

Exclusion criteria: ASA III and IV Uncooperative patients Allergy to local anesthesia Patient refusal of local anesthesia Coagulopathy or history of anticoagulant therapy Orbital deformity Patients with excessive tremors or agitations

Design outcomes

Primary

Measure	Time frame
The onset of globe akinesia;The onset of lid akinesia ;The intraocular pressure	—

Secondary

Measure	Time frame
The duration of analgesia;The duration of motor block;The vital data including the heart rate, oxygen saturation, and blood pressure;Patient and surgeon satisfaction ;complications including lid hematoma or subconjunctival hemorrhage	—

Countries

Egypt

Contacts

Public ContactIbrahim Elbanna

Anesthesia Surgical Intensive Care and Pain Management Research Institute of Ophthalmology

Ibrahimhassan2002@hotmail.com+201009181878

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026