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Comparing the Benefits of Dexamethasone and Bupivacaine in Spinal Anesthesia for Orthopedic Surgery

Effectiveness of dexamethasone as adjuvant to intrathecal bupivacaine versus bupivacaine alone in spinal anaesthesia among orthopedic surgery patient at KCMC Hospital, 2024

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202411679781198
Enrollment
96
Registered
2024-11-15
Start date
2024-12-02
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery

Interventions

Case or experimental will be given intrathecal bupivacaine with dexamethasone as adjuvant
Standard Treatment

Sponsors

KCMC Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1 Inclusion criteria ? Patients classified as American Society of Anesthesiologist (ASA) class I-II, ? Planned to undergo lower extremity orthopedic surgery under Spinal Anesthesia ? Patient who consented. ? Patients with age 18 years and above.

Exclusion criteria

Exclusion criteria: Exclusion Criteria ? Patients who are contraindicated to spinal anesthesia. ? Fluid restriction. ? History of using steroid therapy for a long time. ? Chronic pain or daily intake of analgesic.

Design outcomes

Primary

MeasureTime frame
The effectiveness of dexamethasone as an adjuvant to intrathecal bupivacaine versus bupivacaine alone in orthopedic surgery will be determined primarily by the total duration of sensory and motor blockade. The duration of the sensory block was defined from the peak of the sensory block up to when the patient complained of pain at the surgery site. Motor block duration is from the peak of the motor block (Bromage scale score 3) to the complete recovery of motor function (Bromage scale score 0).

Secondary

MeasureTime frame
The supportive outcome measures on investigating the effectiveness of dexamethasone as an adjuvant to intrathecal bupivacaine in orthopedic surgery will be as follows. ? Pain score postoperative using a Numerical Rating Scale (NRS) ? Time for First Postoperative analgesia.

Countries

United Republic of Tanzania

Contacts

Public ContactAlex Lwiza

Medical specialist

lxlwiza@gmail.com+255712393947

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026