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Role of Transcranial Doppler to predict incidence and outcome of sepsis associated encephalopathy

Role of Transcranial Doppler to predict incidence and outcome of sepsis associated encephalopathy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202410707982429
Enrollment
93
Registered
2024-10-07
Start date
2023-08-01
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases

Interventions

trans cranial doppler done by us probe

Sponsors

Riham naser saied sherif
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients 18 -60 years of age admitted to ICU. 2. Patients manifesting clinically with sepsis or septic shock state and admitted to ICU within 24 hours of sepsis diagnosis. 3. Patients with Glasgow coma scale =13.

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Abnormal brain pathology at CT Brain: intracranial hemorrhage (ICH), stroke, hydrocephalous, brain tumor. 3. Patients with other metabolic causes of encephalopathy: uremic encephalopathy, hepatic encephalopathy, hypoglycemia. 4. Electrolyte imbalance e.g., hyponatremia, hypernatremia, hypokalemia. 5. CNS infection e.g., meningitis and encephalitis 6. Patients with severe carotid stenosis > 70%. 7. Patients on sedation, alcoholic, or drug toxicity that can affect consciousness. 8. Patients with psychiatric disorders e.g: Alzheimer-dementia.. etc

Design outcomes

Primary

MeasureTime frame
Assessment of the correlation between serial transcranial doppler (TCD) and incidence of sepsis-associated encephalopathy in patients with septic shock.

Secondary

MeasureTime frame
Assessment of the correlation between the TCD parameters in septic shock and Length of ICU stay and in-hospital mortality rates.

Countries

Egypt

Contacts

Public ContactHala Mohamed Koptan

Lecturer of Anesthesia Intensive Care and Pain Management at Menofia faculty of medecine

halakoptan@yahoo.com01227305322

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026