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Clinical Efficacy of L-Carnitine in Pediatric Heart Failure due to congenital heart disease: Cardiac and Nutritional Perspectives.

Clinical Efficacy of L-Carnitine in Pediatric Heart Failure due to congenital heart disease: Cardiac and Nutritional Perspectives.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202410595634101
Enrollment
45
Registered
2024-10-28
Start date
2024-11-20
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neonatal Diseases Nutritional, Metabolic, Endocrine Paediatrics Cardiology

Interventions

L carnitine supplementation

Sponsors

Shahinaz gamal
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Age: childern under the age of 18 years. 2) Gender : both sexes will be included . 3) Full term. 4) Malnourished patients with controlled heart failure due to congenital heart disease according to NYHA class I and II (New York Heart Association, 1994) and Ross class I and II (Ross ., 2012).

Exclusion criteria

Exclusion criteria: 1) Patients with chromosomal abnormalities and other congenital malformations than cardiac anomalies or other comorbid diseases affecting the growth or the nutritional status of the children 2) Patients with complex cyanotic congenital heart disease such as Truncus arteriosus, TGA (Transposition of great arteries). 3) Patients born prematurely (<36 weeks gestation) or low birth weight 4) Patients with heart failure secondary to diseases other than CHD such as dilated cardiomyopathy, Hypertrophic cardiomyopathy. 5) Uncontrolled patients with severe disease requiring admission at the time of assessment 6) Postoperative patients. 7) Refusal to participate in the study.

Design outcomes

Primary

MeasureTime frame
Effect of L-Carnitine supplementation on the nutritional status, improvement of the cardiac function and frequency of hospitalization in malnourished children with controlled heart failure secondary to CHD .;Effect of L-Carnitine supplementation on the nutritional status, improvement of the cardiac function and frequency of hospitalization in malnourished children with controlled heart failure secondary to CHD

Secondary

MeasureTime frame
Prevalence of malnutrition in children with controlled heart failure 2ndry to CHD ;Correlation between the type of CHD and presence of HF with the severity of malnutrition

Countries

Egypt

Contacts

Public ContactShahinaz Mansour

Specialist of pediatrics

Shahi.gamal@gmail.com01200009604

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026