Assessment of Drug and Diagnostic Resistance Signature in Plasmodium falciparum: Implications on Strategies for Malaria Control in Nigeria

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202410538749711

Enrollment

1100

Registered

2024-10-25

Start date

2025-05-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria

Interventions

Not applicable

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • Children from 6 months to 12 years, who present with malaria symptoms (fever, history of fever in the last 48 hours, within the selected health facilities. • Willingness to give assent/consent to partake in the study. Consent will be taken from the parent or guardians

Exclusion criteria

Exclusion criteria: • Asymptomatic (absence of fever, history of fever in the past 48 hours, or any other symptoms/signs indicating the presence of malaria) • Unwillingness to participate in the study or comply with the study protocol

Design outcomes

Primary

Measure	Time frame
Generating parasite genetic data to support reviews of drug and diagnostic policy in Nigeria. In addition, genomic capacity building and technology transfer for tracking malaria parasites using portable ONT sequencing in Nigeria	—

Secondary

Measure	Time frame
Parasite density measured by qPCR and/or microscopy, among children with suspected false-negative HRP2 RDT results	—

Countries

Nigeria

Contacts

Public ContactAdebanjo Adegbola

Senior Lecturer Obafemi Awolowo University

adegbolaaj@oauife.edu.ng+2348035816301

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026