Circulatory System Surgery
Conditions
Interventions
Placebo group
Sponsors
Esan Babatunde Ayodeji
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Consenting women with uterine fibroid scheduled for primary abdominal myomectomy.
Exclusion criteria
Exclusion criteria: i. Women with previous abdominal surgery (previous myomectomy, caesarean delivery). ii. Women who have allergy or hypersensitivity to Tranexamic acid. iii. Women with chronic medical disorders like hypertension, cardiac and pulmonary diseases, chronic endocrine or metabolic diseases such as diabetes, obesity (body mass index >30kg/m2). iv. Patients with bleeding disorder or abnormal/ borderline clotting profile. v. Patient who has received preoperative hormonal therapy (such as GnRH analogue or oral contraceptives pills) that could affect the intra operative bleeding and the duration of operation. vi. Patient who declines participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| estimation of total blood loss at surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| • Operation time in minute from skin incision to skin closure. • Myomectomy time in minute starting from first uterine incision to closure of last uterine incision. • Postoperative stay in hospital in days. • Adverse effects of tranexamic acid (thromboembolic incidents, gastrointestinal upset in the form of nausea and vomiting). • The need for blood transfusion either intra operation or post operation. | — |
Countries
Nigeria
Contacts
Public Contactjoyce esan
nursing lecture
Outcome results
None listed