Neuromuscular training in highly trained female soccer players

Preseason neuromuscular versus endurance training leads to greater improvements in isokinetic strength, muscle damage, and inflammation parameters in highly trained female soccer players

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202409922230803

Enrollment

Registered

2024-09-02

Start date

2023-08-19

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nutritional, Metabolic, Endocrine

Interventions

Neuromuscular training

Endurance training

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: - Highly trained female soccer players - Aged under 19 years old

Exclusion criteria

Exclusion criteria: - Age >19 years old - Injured players - Goalkeepers players

Design outcomes

Primary

Measure	Time frame
This study, aimed to examine the impact of a preseason neuromuscular training program versus an endurance training program on isokinetic muscle strength and blood markers in highly trained female soccer players. The primary outcomes are determined pre- and post-intervention.	—

Secondary

Measure	Time frame
Blood samples were taken pre- and post-training to analyze markers of muscle damage (CK and LDH) and inflammation (CRP and IL-6). The first blood sample was taken prior to the start of the study and the second sample at the end of the six-week training program. Venous blood samples (15 ml) were collected in the morning (between 9:00 a.m. and 10:30 a.m., after an overnight fast and without exercise for 12 h) from an antebrachial arm vein, using a standard venipuncture technique collected with an ethylenediaminetetraacetic acid (EDTA) tube. Samples were centrifuged for 10 minutes at 4°C and 3000 rpm to obtain plasma, and CRP, CK, and LDH activities were determined using a multiparametric analyzer (Konelab 30TM, Thermo Electron Corporation, Holliston, USA). CRP activity was determined using an immunoturbidimetry method, with an intra-assay coefficient of variation of 1.7% for the CRP kit. CK activity was determined with a UV method (IFCC) using N-acetyl-cysteine, and the intra-assay coefficient of variation for the CK kit was 1.8%. LDH activity was determined by applying the enzymatic rate method (IFCC), with an intra-assay coefficient of variation of 1.1% for the LDH. The secondary outcomes are determined pre- and post-intervention.	—

Measure

Time frame

Blood samples were taken pre- and post-training to analyze markers of muscle damage (CK and LDH) and inflammation (CRP and IL-6). The first blood sample was taken prior to the start of the study and the second sample at the end of the six-week training program. Venous blood samples (15 ml) were collected in the morning (between 9:00 a.m. and 10:30 a.m., after an overnight fast and without exercise for 12 h) from an antebrachial arm vein, using a standard venipuncture technique collected with an ethylenediaminetetraacetic acid (EDTA) tube. Samples were centrifuged for 10 minutes at 4°C and 3000 rpm to obtain plasma, and CRP, CK, and LDH activities were determined using a multiparametric analyzer (Konelab 30TM, Thermo Electron Corporation, Holliston, USA). CRP activity was determined using an immunoturbidimetry method, with an intra-assay coefficient of variation of 1.7% for the CRP kit. CK activity was determined with a UV method (IFCC) using N-acetyl-cysteine, and the intra-assay coefficient of variation for the CK kit was 1.8%. LDH activity was determined by applying the enzymatic rate method (IFCC), with an intra-assay coefficient of variation of 1.1% for the LDH. The secondary outcomes are determined pre- and post-intervention.

—

Countries

Morocco

Contacts

Public ContactClaire Tourny

Professor Univeristy of Rouen

claire.tourny@univ-rouen.fr+33683427272

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026