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A Double-Blinded Randomized Controlled Trial Comparing Genicular Nerve Blockade using Corticosteroids Versus Phenol in management of Knee Osteoarthritis Pain in Yaoundé

A Double-Blinded Randomized Controlled Trial Comparing Genicular Nerve Blockade using Corticosteroids Versus Phenol in management of Knee Osteoarthritis Pain in Yaoundé

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202409901377562
Enrollment
60
Registered
2024-09-19
Start date
2023-06-05
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases

Interventions

Sponsors

Universite Catholique de Louvain
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Age 18 years or above at the time of the study - Chronic knee pain greater than 3 months, with NRS > 5/10; - Diagnosis of knee osteoarthritis (confirmed by the report of a radiologist), stage 2 to 4 of Kellgren–Lawrence; - No scheduled knee surgery in the last 03 months - Patient having benefited from at least one well-conducted conservative treatment (NSAIDs, Visco-supplementation, Corticosteroids, physiotherapy, etc.) without satisfaction for 1month

Exclusion criteria

Exclusion criteria: - Acute knee pain with signs of local inflammation - Skin lesions at treatment sites - Visco-supplementation or corticosteroid therapy carried out less than 3 months previously - Known connective tissue disease of the knee - Follow-up for neuropsychiatric disorders - Anticoagulant treatment in progress - Cardiac pacemaker - Poor physical condition - Physical disability - Patient with complex regional pain syndrome

Design outcomes

Primary

MeasureTime frame
-Knee pain: NRS -Knee function: WOMAC score and Oxford Knee Score (OKS) -Pain medication Consumption: Quantitative Analgesic Questionnaire (QAQ) -Quality of life : SF-12 questionnaire, PROMIS questionnaire -Central Sensitization Inventory -Quantitative analysis of walking (QAW)

Secondary

MeasureTime frame
- D1: NRS, AQM - D2: NRS, QAQ - D30: NRS, WOMAC, OKS, QAQ, SF-12, PROMIS - D90: NRS, WOMAC, OKS, QAQ, SF-12, PROMIS - D360: NRS, WOMA, OKS, QAQ, SF-12, PROMIS

Countries

Cameroon

Contacts

Public ContactGaspary Fodjeu

University of Yaounde 1 and Universite Catholique de Louvain

gaspa112@yahoo.com00237675794506

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026