Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients of both sexes American Society of Anesthesiologists (ASA) physical status I – II Aged from 35 - 65 years
Exclusion criteria
Exclusion criteria: Patients who had any contraindications to spinal or epidural anaesthesia ( Infection at the site of insertion, Spine surgery or deformity at injury level, thrombocytopenia, coagulopathy) Refusing spinal or epidural anesthesia Psychotic or difficult communication Allergy to dexmedetomidine or to local anesthetics Patients with decompensated renal and hepatic diseases or major respiratory disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| First analgesic request starting from injection time . | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Total postoperative analgesic requirement. 2. Intraoperative non-invasive blood pressure (NIBP) and heart rate (HR) every 30 min all over the operation time and at 1, 6, 12, 24 hours after recovery. 3. Patient’s pain score was assessed using visual analogue scale (VAS): scored from 0–10 (where 0=no pain and 10=the worst pain imaginable). 4. Postoperative side effects as bradycardia, hypotension, desaturation and vomiting incidence during recovery and 1st 24 hours. 5.Maximum block level: By Modified Bromage Score (Time frame; basal and every 2 hours for the next 6 postoperative hours after recovery) 6.Complication: • Nausea, vomiting and visceral pain. • post dural puncture headache. • Hospital stay time. • ICU admission rate | — |
Countries
Egypt
Contacts
Lecturer of Anesthesia surgical Intensive Care