Effect of Selenium and Citicoline vs Zinc and Citicoline vs Citicoline Only on Postoperative Brain Tumor Excision in the ICU

Effect of Selenium and Citicoline versus Zinc and Citicoline versus Citicoline Only on Postoperative Brain Tumor Excision in the ICU

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202409776910334

Enrollment

144

Registered

2024-09-18

Start date

2024-10-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Nervous System Diseases

Interventions

Citicoline only

Selenium and Citicoline supplementation.

Zinc and Citicoline supplementation.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 18-70 years. Undergoing brain tumor excision. Admitted to the ICU postoperatively

Exclusion criteria

Exclusion criteria: Severe systemic illness. Pre-existing cognitive impairments. Known allergies to study supplements

Design outcomes

Primary

Measure	Time frame
The assessment of cognitive function using the Montreal Cognitive Assessment (MoCA) scale at baseline (preoperatively), on postoperative days 7 and 14, and at a 3-month follow-up	—

Secondary

Measure	Time frame
Levels of inflammatory markers (e.g., CRP, ESR) measured at baseline, postoperative days 3, 7, and 14 incidence of delirium. length of ICU stay	—

Countries

Egypt

Contacts

Public Contactahmed abdelwahab

assistant lecturer of neurosurgery

ahmedmohamed95@mans.edu.eg00201023425946

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026