Effect of Strepsils on Postextubation Sore Throat, Cough and Hoarseness after Endoscopic Retrograde Cholangiopancreatography.

Effect of Preoperative Strepsils Lozenges on Incidence of Postextubation Sore Throat, Cough and Hoarseness after Endoscopic Retrograde Cholangiopancreatography Procedures.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

PACTR

Registry ID

PACTR202409618171064

Enrollment

Registered

2024-09-16

Start date

2023-04-02

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery Anaesthesia

Interventions

group Strepsils

The control group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: • 20 -65 years old patients from either gender. • Scheduling for elective ERCP under general anesthesia and endotracheal intubation. • patients who expected to remain in the hospital for at least 24 hours

Exclusion criteria

Exclusion criteria: • Patients with sore throat for any reason or obvious hoarseness • Patients with upper respiratory tract infection in past 2 weeks. • History of smoking or asthmatic patient. • Refusal to participate in the study. • Patients undergoing surgeries of the oral cavity and pharynx • More than two attempts at intubation, • use of nasogastric tube or throat packs, • Anticipated rapid-sequence induction or airway difficulty (Mallampatti Grade III and IV) • surgical duration of >120 min • Patients on steroid therapy or History of hypersensitivity to the drug or to opioids. • Body Mass Index > 30 kg/m2,Gastroesophageal reflux disease.

Design outcomes

Primary

Measure	Time frame
The incidence and severity of sore throat after the ERCP procedure	—

Secondary

Measure	Time frame
• The incidence of cough and hoarseness of voice after the procedure. • Identification of risk factors for each complication after ERCP • the procedure time, intraprocedural hemodynamics and complication as well as the incidence of bucking, coughing during extubation • The duration of laryngoscopy, number of intubation attempts, Cormack-Lehane laryngoscopic view, difficulty of endoscope intubation and presence of orotracheal bleeding	—

Measure

Time frame

• The incidence of cough and hoarseness of voice after the procedure. • Identification of risk factors for each complication after ERCP • the procedure time, intraprocedural hemodynamics and complication as well as the incidence of bucking, coughing during extubation • The duration of laryngoscopy, number of intubation attempts, Cormack-Lehane laryngoscopic view, difficulty of endoscope intubation and presence of orotracheal bleeding

—

Countries

Egypt

Contacts

Public ContactWaleed Mohamed Rifaat

Assistant Prof of Anesthesia and surgical ICU Faculty of Medicine Mansoura University Egypt

dr_tarekhabeeb@yahoo.com+01005663554

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026