Digestive System
Conditions
Interventions
Pilates and dietary advice
Sponsors
Cairo University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. They were under medical supervision. 2. Age between 20 to 45 years. 3. Ability to perform exercises. 4. Diagnosis of IBS will be based on Rome IV Diagnostic criteria. 5. Baseline irritable bowel syndrome severity score (moderate to severe)>174
Exclusion criteria
Exclusion criteria: 1.Organic gastrointestinal disorders or other organic disease hindering physical activity. 2. Treatment with steroids, antibiotics, immunosuppressants for at least 6 months before the beginning of the study. 3. A history of resection of the stomach, small intestine, or large intestine (excluding hernia repair, appendectomy (> 3 months) or resection of benign polyps). 4. Concurrent infectious enteritis, hyperthyroidism, hypothyroidism, or other diseases that may affect gastrointestinal transit or colonic function. 5. Malignant tumors. 6. Concurrent serious cardiovascular, respiratory, renal, hepatic, gastrointestinal (excluding IBS).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (tumor necrosis factor alpha ) Serum levels of tumor necrosis factor alpha (TNFa) were measured using an enzyme-linked immunosorbent assay (ELISA) | — |
Secondary
| Measure | Time frame |
|---|---|
| malondialdehyde MDA Tiobarbituric acid method were used for measuring serum malondialdehyde (MDA) level | — |
Countries
Egypt
Contacts
Public ContactHeba Abd El Ghafar
assistant professor
Outcome results
None listed