The impact of Perioperative Dexmedetomidine usage in prevention of Acute Kidney Injury in patients undergoing Whipple operations

The impact of Perioperative Dexmedetomidine usage in prevention of Acute Kidney Injury in patients undergoing Whipple operations ( randomized control study )

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202408886014501

Enrollment

Registered

2024-08-12

Start date

2024-04-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

control

dexmeditomidine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients (18 years or older) undergoing Whipple surgery.

Exclusion criteria

Exclusion criteria: Patients with pre-existing renal dysfunction (eGFR <60 mL/min/1.73 m2) Major intraoperative events (e.g. severe hemodynamic instability, massive blood loss, massive blood products transfusion). Allergy to Dexmedetomidine, unwilling to participate in the study will be excluded.

Design outcomes

Primary

Measure	Time frame
renal function tests urea and creatinine	—

Secondary

Measure	Time frame
Urine output in the first 24 hours postoperatively. Incidence of delirium, hypotension, bradycardia, and prolonged mechanical ventilation within 48 hours postoperatively	—

Countries

Egypt

Contacts

Public Contacthanaa rashed

anasthesia lecturer

hanaarashed2020@yahoo.com01001378542

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026