Foley catheter versus laminaria for cervical preparation prior to second trimester dilation and evacuation: Open label a non-inferiority randomized trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

PACTR

Registry ID

PACTR202408852551318

Enrollment

128

Registered

2024-08-01

Start date

2024-07-22

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion

Interventions

Cervical preparation with Foley catheter prior to second trimester D and E

Laminaria

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: -Women undergoing second trimester D&E -Gestational age at 16-22 weeks -Volunteering to participate in the study Elective D&E procedure

Exclusion criteria

Exclusion criteria: -Incomplete abortion -Molar pregnancy

Design outcomes

Primary

Measure	Time frame
Mean dilation and evacuation- D&E -procedure time (in minutes) after overnight laminaria or Foley catheter placement	—

Secondary

Measure	Time frame
requirement of additional doses of misoprostol ( 2 or more doses) , Foley or Laminaria insertion to D&E time, D&E complications ( hemorrhage, cervical tear, infection, uterine perforation , failed cervical preparation, and incomplete abortion ), and patient acceptability of the cervical preparation methods	—

Countries

Ethiopia

Contacts

Public ContactAbraham Fessehaye Sium

SPHMMC

abrahamfessehaye4@gmail.com+251929123745

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026