Respiratory
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1- Adult patients, aged between 18 to 65 years. 2- Patient who are mechanically ventilated more than 48 hours and meet all the following criteria for spontaneous breathing trial: • Resolution or improvement of the disease leading to MV, • adequate oxygenation indicated by arterial oxygen saturation (SaO2)>90% with inspired oxygen fraction (FiO2) =0.5, or arterial oxygen partial pressure to inspired oxygen fraction (PaO2/FiO2)=150 mmHg, both with positive end-expiratory pressure (PEEP)=8 cmH2O, • respiratory rate=30 breaths/min, • intact cough reflex • hemodynamic stability in low dose or absence of vasopressors.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1- Pregnancy 2- Thoracostomy or pneumothorax 3- Flail chest or rib fracture 4- Neuromuscular disease 5- Diaphragmatic paralysis 6- Cerebrovascular stroke with bulbar symptoms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: To determine the predictive value of diaphragmatic rapid shallow breathing indices in successful weaning from the ventilator. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome: Correlation between the diaphragmatic indices and days of invasive mechanical ventilation, length of stay in the ICU and ICU mortality. | — |
Countries
Egypt
Contacts
Assistant professor of Anesthesiology Intensive Care and Pain Management