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Preemptive ketamine versus dexmedetomidine in decreasing oculo-cardiac reflex in pediatric strabismus surgery.

Effect of Pre-emptive Intravenous Ketamine versus Dexmedetomidine on Oculocardiac Reflex (OCR) Among Schoolchildren during Strabismus Surgery: A Randomized Controlled Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202408666586819
Enrollment
87
Registered
2024-08-15
Start date
2024-06-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Sponsors

Authors
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Schoolchildren patients aged 6-18 years old Both sexes Scheduled for strabismus surgery Classified as class I or II according to the American Society of Anesthesiologists (ASA) physical status score

Exclusion criteria

Exclusion criteria: Legal guardians’ refusal Allergy to study drugs or contraindications for the use of them ASA physical status class lll or higher Patients with Severe cardiovascular disease; preoperative bradycardia or preoperative atrioventricular block on clinical examination. Patients with mental illness (history/medical record) or with a developmental delay or neurological disease. Children having a cardiac pacemaker, or taking any heart rate modifying drugs.

Design outcomes

Primary

MeasureTime frame
Any intraoperative decrease in HR of equal to or more than 20% on pulse oximetry and ECG or presence of arrhythmias in the form of ventricular ectopy, ventricular fibrillation or AV block on ECG.

Secondary

MeasureTime frame
Postoperative Wong–Baker Faces Pain Rating Scale score;The incidence and number of episodes of vomiting ;The incidence of postoperative desaturation

Countries

Egypt

Contacts

Public ContactMohammed Nashaat

Lecturer of Anesthesia and surgical intensive care

Moh_nashaat@mans.edu.eg01092323198

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026