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A Comparative Study Between Dexmedetomidine versus Magnesium Sulphate for Controlled Hypotensive Anesthesia in Rhinoplasty Surgeries.

A Comparative Study Between Dexmedetomidine versus Magnesium Sulphate for Controlled Hypotensive Anesthesia in Rhinoplasty Surgeries.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202408620568675
Enrollment
42
Registered
2024-08-08
Start date
2022-07-20
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

Dexmedetomidine
magnesium sulphate

Sponsors

Primary Sponsor
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1-Patients of American Society of Anaesthesiologists (ASA) physical status I and II 2-Patients of both sex having age group between 18-60 years old electively scheduled for rhinoplasty under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Refusal of the procedure or participation in the study. 2. Intraoperative hemodynamic instability. 3. Patients who require awake intubation. 4. Patients having hypertension or ischemic heart disease. 5. Patients with heart block, hepatic, renal and cerebral impairment, or with known coagulopathies. 6. Patients having history of allergy to the study drug used. 7. Patients on ACE inhibitors, a-2 adrenergic receptor blockers, Calcium channel blockers or beta blockers.

Design outcomes

Primary

MeasureTime frame
1.Heart rate. 2.Mean arterial blood pressure.

Secondary

MeasureTime frame
1-Surgical field will be assessed by the surgeon in terms of bleeding and visibility. 2-During postoperative period, the 2 groups will also be compared accordingly for the occurrence of the side effects as bradycardia, shivering, nausea, and vomiting to assess each drug effects on these side effect

Countries

Egypt

Contacts

Public Contactsarah abdelhalem

assistant lecturer of Anesthesia and intensive care at faculty of Medicine Ain Shams University

sarahabdelhalem@hotmail.com+201060702202

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026