Anaesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: patients aged 65 years old or more both sexes the ASA class I or II undergoing elective surgeries under general anesthesia and not more than 1 hour.
Exclusion criteria
Exclusion criteria: Patients on opioid therapy, central nervous system depressants, or with physical dependence on opioids , cardiac, hepatic, or renal disease, pregnancy or lactation, diabetes mellitus, bronchial asthma, and/ or bleeding disorder are not included. We will also exclude patients with established respiratory depression; a history of hypersensitivity to one of the drugs, and/or not willing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative ephedrine consumption | — |
Secondary
| Measure | Time frame |
|---|---|
| the occurance of post induction hypotension, bradycardia, and hypertension (defined as increased mean arterial pressure by >20% of the baseline reading), mean arterial pressure and heart rate. | — |
Countries
Egypt
Contacts
assistant professor of anesthesia and intensive care and pain management