laparoscopic hysterectomy
Conditions
Interventions
Group B Bupivacaine HCL Marcaine alone n 15
Group A Bupivacaine HCL Dexmedetomidine Precedex n 15
Sponsors
Ain Shams University Maternity Hospital and Adam International Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: patients indicated for laparoscopic hysterectomy at our hospital for any gynecological indication
Exclusion criteria
Exclusion criteria: 1- history of chronic opioid intake (due to opioid-induced tolerance &Hyperalgesia). 2-large Uterus (= 12 gestational week), which could lead to surgical difficulties. 3- renal failure (bupivacaine contraindicated in RF due to the hypotension). 4-chronic alcoholism (increase dose requirement of local anesthesia). 5- heart block (due to bupivacaine side effect of cardiotoxicity) 6-history of left ventricular failure (due to bupivacaine side effect of cardiotoxicity and hypotension). 7- patients taking beta-blocking drugs (due to bupivacaine side effect of hypotension) 8-allergy to the study drugs. 9-patient is enrolled in another pain management study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome: Postoperative pain scores in the first 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| The Secondary outcomes: nausea and Vomiting, the need for post-operative rescue analgesia 1st 24 hours, and length of hospital stay | — |
Countries
Egypt
Contacts
Public ContactAhmed Sherif
lecturer obestatrics and gynecology Ain Shams University
Outcome results
None listed