Effects of Very Early Exercise Intervention on Blood Biomarkers and Short-term Clinical Outcomes in Patients with Ischaemic Stroke- A Randomized Clinical Trial

Conditions

Nervous System Diseases

Adekola B. Ademoyegun, Oluwatobi I. Awogboro, Emmanuel Ojo, Adebukola G. Ibitoye, Marufat Oluyemisi Odetunde et al. (6 authors)

Bulletin of Faculty of Physical Therapy2025-10-13

10.1186/s43161-025-00324-9

Effects of very early exercise on inflammatory markers and clinical outcomes in patients with ischaemic stroke- a randomized controlled trial.

Ademoyegun AB, Awotidebe TO, Odetunde MO, Inaolaji SO, Bakare SO, Azeez FW, Olayemi O.

2025-03-211 citations

10.1186/s12883-025-04132-5

Association of baseline plasma fibrinogen levels with cognitive and affective status at 30 and 90 days in individuals with ischemic stroke: A prospective study from Nigeria

Adekola B. Ademoyegun, Taofeek O. Awotidebe, Marufat Oluyemisi Odetunde, Samuel O. Inaolaji, Serifat O. Bakare et al. (7 authors)

Brain Circulation2024-10-012 citations

10.4103/bc.bc_52_24

Interventions

Usual care

Early Exercise Intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The participants for this study included patients: i. with clinical and radiological diagnosis (Computed Tomography Scan) of acute ischaemic stroke. ii. who were 40 years and older. iii. who were admitted to the hospital within 24 hours after the incidence of stroke. iv. with no major communication problem preventing them from understanding the protocol.

Exclusion criteria

Exclusion criteria: Participants excluded from the study were patients: i. that were in the intensive-care unit and/or patients with altered state of consciousness by having the problem of consciousness with =2 score on item one of National Institute of Health Stroke Scale (NIHSS). ii. with severe stroke having NIHSS scores>15 iii. with a score more than 0 on modified ranking scale before stroke or with any apparent physical disability before stroke onset. iv. with other type of stroke (haemmorhagic stroke).

Design outcomes

Primary

Measure	Time frame
Interleukin-6, Fibrinogen, leucocytes, neutrophils, and lymphocytes	—

Secondary

Measure	Time frame
Global disability, Motor impairment, functional independence, depression, anxiety, and cognition	—

Countries

Nigeria

Contacts

Public ContactSamuel Inaolaji

Physiotherapist Osun State University Teaching Hospital

jideinaolaji2018@gmail.com+2348165597482

Outcome results

None listed