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Efficacy of perioperative inhalational oxytocin on postoperative pain in lower limb fracture surgeries

Efficacy of perioperative inhalational oxytocin on postoperative pain in lower limb fracture surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202406682157896
Enrollment
36
Registered
2024-06-28
Start date
2024-06-20
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases

Interventions

oxytocine group

Sponsors

Mansoura university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age from 18 to 45 years old. 2. ASA of class I and II. 3. Both sexes.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Uncontrolled Psychiatric diseases. 3. Known intolerance to the study drugs. 4. Unstable cardiovascular condition.

Design outcomes

Primary

MeasureTime frame
Total postoperative morphine requirement in the 1 st 72 hours postoperative.

Secondary

MeasureTime frame
1. Time to the first request of morphine rescue analgesia. 2. visual analogue scale score 2, 4, 6, 12, 24, 48, 72 hours postoperative. 3. Perioperative hemodyamics (MAP - HR). 4. Postoperative side effect as nausa, vomiting.

Countries

Egypt

Contacts

Public ContactKarim Awad

lecturer of anesthesia and surgical icu

Dr.karimali2010@mans.edu.eg+201004209702

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026