Uterine fibroids
Conditions
Interventions
Tourniquet plus Intravenous Tranexamic Acid
Tourniquet plus vaginal misoprostol
Sponsors
Dr Ogwu Robinson
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion Criteria I. Patients who had open abdominal myomectomy for uterine fibroids. II. Patients with pre-operative haemoglobin levels greater than or equal to 10g/dl III. Patients who gave written informed consent. IV. Patients who were willing to accept blood transfusion. V. Patients who were willing to accept Tranexamic Acid or Vaginal Misoprostol.
Exclusion criteria
Exclusion criteria: Exclusion Criteria I. Patients with known bleeding/ clothing disorder like thrombocytopenia with increased risk of bleeding. II. Patients with known allergic reaction to Tranexamic Acid or Misoprostol. III. Patients with any prior pelvic surgeries, such as previous myomectomy or Caesarean Section with increased risk of adhesions, prolonged surgery and bleeding. IV. Patients with co-existing endometriosis or adenomyosis from clinical history or findings from investigations. V. Patients with medical co-morbidity such as cardiac or renal disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The blood loss at surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| i. Need for blood transfusion in any of the participants in either arm of the study. ii. Any adverse drug reactions in any of the participants in either of the study arm. | — |
Countries
Nigeria
Contacts
Public ContactRobinson Ogwu
Principal Investigator and Consultant Obstetrician and Gynaecologist
Outcome results
None listed