Ultrasound guided thoracoabdominal nerves through perichondral approach block versus posterior quadratus lumborum block for postoperative analgesia in adult patients undergoing abdominoplasty surgeries

Ultrasound guided thoracoabdominal nerves through perichondral approach block versus posterior quadratus lumborum block for postoperative analgesia in adult patients undergoing abdominoplasty surgeries: A randomized controlled clinical trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202406526378498

Enrollment

Registered

2024-06-06

Start date

2023-06-01

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anaesthesia

Interventions

TAPA block

QL block

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Status I or II Both males and females Age 18 to 60 years old Body mass index > 35 kg/m2 Scheduled for abdominoplasty under general anesthesia

Exclusion criteria

Exclusion criteria: American Society of Anesthesiologists Physical Status III or IV Patient’s refusal Patients age above 60 or below 18 years Allergy to the study drugs A history of chronic pain Psychiatric comorbidity Scheduled opioid pain medication or neuroleptic drugs Bleeding disorders (medication induced i.e., coumadin; or genetic i.e. hemophilia; or acquired i.e. DIC) Pregnancy or breastfeeding Infection at block puncture site

Design outcomes

Primary

Measure	Time frame
Patient-assessed resting and movement-induced pain using the Numeric Rating Scale	—

Secondary

Measure	Time frame
Intraoperative heart rate and blood pressure;Intraoperative fentanyl consumption;Postoperative nalbuphine consumption;Postoperative heart rate and blood pressure;Incidence of adverse effects, such as postoperative nausea and vomiting, injury to surrounding structures, failed block and local anesthetic toxicity;Patient satisfaction regarding their experience with the analgesic management after the surgery using the verbal rating scale, 5 = very satisfied, 4 = satisfied, 3 = neutral, 2 = dissatisfied and 1 = very dissatisfied ;Block performance time in minutes from probe contact with the skin until the needle was withdrawn;The level of sensory block using a cold, wet cotton swab, comparing the nerve areas on the surgical side to the contralateral area. Sensitivity to cold is graded on a scale of 0 to 2 (2: normal sensitivity to cold, 1: hypoesthesia; and 0: anesthesia);Time to first rescue analgesia	—

Measure

Time frame

Intraoperative heart rate and blood pressure;Intraoperative fentanyl consumption;Postoperative nalbuphine consumption;Postoperative heart rate and blood pressure;Incidence of adverse effects, such as postoperative nausea and vomiting, injury to surrounding structures, failed block and local anesthetic toxicity;Patient satisfaction regarding their experience with the analgesic management after the surgery using the verbal rating scale, 5 = very satisfied, 4 = satisfied, 3 = neutral, 2 = dissatisfied and 1 = very dissatisfied ;Block performance time in minutes from probe contact with the skin until the needle was withdrawn;The level of sensory block using a cold, wet cotton swab, comparing the nerve areas on the surgical side to the contralateral area. Sensitivity to cold is graded on a scale of 0 to 2 (2: normal sensitivity to cold, 1: hypoesthesia; and 0: anesthesia);Time to first rescue analgesia

—

Countries

Egypt

Contacts

Public ContactAhmed Mohamed

Department of Anesthesia Surgical ICU and Pain Management Faculty of Medicine Cairo University

dr.ahmedkar@gmail.com+201009750511

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026