Effect of probiotics on quality of life and nutritional status in spinal cord injury: A controlled, randomized, double-blind study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202405750001803

Enrollment

Registered

2024-05-02

Start date

2024-06-02

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System Haematological Disorders Mental and Behavioural Disorders Nervous System Diseases Nutritional, Metabolic, Endocrine

Interventions

Probiotic Effect

Probiotic effect

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age over 18 years Presence of a spinal cord injury whether complete or incomplete, of traumatic or non-traumatic origin Evolution of spinal cord injury greater than 1 year

Exclusion criteria

Exclusion criteria: Infection requiring prolonged antibiotic therapy Chronic digestive diseases or history of digestive surgery Paraplegics already followed in psychiatry Pregnant or breastfeeding woman Intolerance to the probiotic used Irregular intake of treatment Intercurrent infection requiring antibiotic therapy Lost to follow-up during the intervention

Design outcomes

Primary

Measure	Time frame
Our primary endpoint is the improvement of the Neurological Bowel Dysfunction Score (NBD score).	—

Secondary

Measure	Time frame
- Quality of life assessment: SF-36 - The Hospital Anxiety and Depression Scale (HADS) - Biological data: CBC, inflammatory profile, nutritional profile, lipid profile, fasting blood glucose	—

Countries

Tunisia

Contacts

Public ContactBassem Tiss

Physical Medicine and Rehabilitation

ettisbassem@gmail.com+216276402

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026