Dormicum- propofol versus dexmedetomidine- propofol versus ketamine- propofol for sedation during lower gastrointestinal endoscopy in patients: a randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202405727585104

Enrollment

Registered

2024-05-31

Start date

2024-06-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive System

Interventions

Ketamine and propofol group

Dormicum and propofol group

Dexmedetomidine and propofol group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. American society of Anesthesiologists physical status grade 1 and grade 2. 2. Age between 16 and 70 years. 3. Both sexes.

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Neuromuscular diseases 3. Hemotalogical diseases 4. Psychiatric diseases

Design outcomes

Primary

Measure	Time frame
The primary outcome is to compare the recovery time when using dormicum- propofol combination to dexmedetomidine- propofol and to ketamine- propofol combination in sedating patients undergoing lower gastrointestinal endoscopy (colonoscopy).	—

Secondary

Measure	Time frame
Secondary outcome 1) Heart rate (HR), respiratory rate (RR), mean arterial pressure (MAP), and peripheral oxygen saturation (SpO2) will be measured every 5 minutes (min) until the procedure completed. 2) Amount of propofol consumption 3) The time required to reach the target Ramsay Sedation Score (RSS) (3–4) is called the induction time. 4) The occurrence of side effects will be recorded as nausa and vomiting	—

Measure

Time frame

Secondary outcome 1) Heart rate (HR), respiratory rate (RR), mean arterial pressure (MAP), and peripheral oxygen saturation (SpO2) will be measured every 5 minutes (min) until the procedure completed. 2) Amount of propofol consumption 3) The time required to reach the target Ramsay Sedation Score (RSS) (3–4) is called the induction time. 4) The occurrence of side effects will be recorded as nausa and vomiting

—

Countries

Egypt

Contacts

Public Contactamani tarbay

lecturer of anesthesia and surgical icu

Amany.tarbay@mans.edu.eg+201002031086

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026