Cardiology
Conditions
Interventions
study group
control group
Sponsors
mahmoud ibrahim
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: The patients will be selected according to the following inclusion criteria: The diagnosis of DCM will be taken by: (i) the lack of history of typical chest pain, (ii) the absence of signs of ischemia or myocardial infarction at the electrocardiogram. (iii) global dilation of both ventricles at the echocardiogram with no regional left ventricular dyskinesia. (iv) the presence of normal thallium scintigraphy and normal coronary angiogram, left ventricular end-diastolic dimension >5.5 cm and end-systolic diameter >4.5 cm, fractional shortening <25% and ejection fraction <45%, sinus rhythm. (v)New York Heart Association (NYHA) class II–III.
Exclusion criteria
Exclusion criteria: The exclusion criteria includes the following; (i)significant coronary disease by history or angiography to exclude ischemic causes, (ii) evidence for secondary causes of cardiomyopathy as long standing or uncontrolled hypertension, (iii) primary valvular disease, atrial fibrillation (AF), severe functional mitral regurgitation (MR) (iv) clinical evidence of pulmonary disease (chronic obstructive lung disease, moderate to severe pulmonary hypertension).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1-Oxygen uptake efficiency slope 2- peak VO2 (ml/kg/min 3- Oxygen uptake efficiency slope 4- 1st degree slope of O2 recovery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1- ejection fraction 2- Kansas City Cardiomyopathy questionnaire (KCCQ) | — |
Countries
Egypt
Contacts
Public Contactsherin hassan mehani
professor
Outcome results
None listed