Comparison of two screening algorithms for tuberculosis among people with clinical risk factors who attend health facilities in Cameroon: a pragmatic cluster-randomized trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202405534532698

Enrollment

72000

Registered

2024-05-02

Start date

2024-05-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tuberculosis

Interventions

Screening for TB with molecular testing

Screening for TB with symptoms

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria for sites (clusters): Provide diagnosis and treatment for TB under supervision of the National TB Program Inclusion criteria for individuals: People who initiate evaluation for TB at an intervention site

Exclusion criteria

Exclusion criteria: Exclusion criteria for sites (clusters): Site administration does not agree for site to participate and be randomized to one of the two interventions for enhanced screening of TB Site treated fewer than 20 people for TB each year (average of last 3 years) Sites are not readily accessible for supervision Exclusion criteria for individuals: People currently on TB treatment People currently on tuberculosis preventive treatment (TPT)

Design outcomes

Primary

Measure	Time frame
Proportion of people with clinical risk factors of TB attending health facilities who have a bacteriologically confirmed TB result and are treated for TB	—

Secondary

Measure	Time frame
Reach, effectiveness, adoption, implementation, and maintenance of these programmatic approaches for TB detection	—

Countries

Cameroon

Contacts

Public ContactCyrille Mbuli

CHPR

cyrillembuli@gmail.com+237674105758

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026