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A comparative study to evaluate the efficacy and tolerability of new generations of iron preparations with traditional iron therapy in pediatrics: A prospective randomized controlled trial.

A comparative study to evaluate the efficacy and tolerability of new generations of iron preparations with traditional iron therapy in pediatrics: A prospective randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
PACTR
Registry ID
PACTR202404915122192
Enrollment
87
Registered
2024-04-05
Start date
2022-06-06
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haematological Disorders Nutritional, Metabolic, Endocrine Paediatrics

Interventions

group 1 by Iron polymaltose complex
group 2 by Liposomal iron
group 3 by Iron Bisglycinate Chelate
group 4 by Micro dispersed iron
group 5 by sun active iron
group 6 by sucrosomial iron

Sponsors

Menoufia faculty of medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Age range 6 months till 59 months old no evidence of infection and negative c–reactive protein (CRP) hemoglobin below the WHO stipulated cutoff values to define IDA anemia: hemoglobin <11.0 g/dL, MCV <73 fL and serum ferritin < 12 mg/L. no history of consumption of iron supplements for 4 months ago or history of blood transfusion.

Exclusion criteria

Exclusion criteria: Children who had any signs of infection (fever, vomiting or diarrhea) on blood collection days, children with anemia rather than IDA e.g. hemolytic anemia or haemoglobinopathy (sickle cell disease, beta thalassemia major) children with chronic diseases or drugs that may affect iron absorption

Design outcomes

Primary

MeasureTime frame
to compare the efficacy and tolerability of oral iron polymaltose complex, Micro dispersed iron, sun active iron, liposomal iron, sucrosomial iron, and iron bisglycinate chelate in treatment of IDA in preschool children aged 6-59 months.

Secondary

MeasureTime frame
to compare their effect on growth.

Countries

Egypt

Contacts

Public ContactHeba El Zefzaf

lecturer

heba_magdy4@yahoo.com00201003717845

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026