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The impact of transcranial direct current stimulation on drug-resistant temporal lobe epilepsy

The effect of transcranial direct current stimulation on drug resistant temporal lobe epilepsy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
PACTR
Registry ID
PACTR202404691765975
Enrollment
30
Registered
2024-04-10
Start date
2020-10-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases

Interventions

Sponsors

Self funded
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Temporal lobe epilepsy patients ages range from 12 up to 40 years, are on two or more correctly prescribed tolerable antiepileptic drugs for more than 12 months with seizure frequency at least four per month. Patients and/or one of their relatives must be cooperative and be able to record the seizure severity and frequency.

Exclusion criteria

Exclusion criteria: - Temporal lobe drug-resistant epileptic patients with a documented history of psychogenic non-epileptic seizures (PNES). - Temporal lobe drug-resistant epileptic patients and having other types of seizures. - Temporal lobe drug-resistant epileptic patients with failed surgical operations. - Temporal lobe drug-resistant epilepsy patients joining other scientific clinical trials.

Design outcomes

Primary

MeasureTime frame
Assessment of the seizure frequency and seizure severity. ;Number of epochs containing epileptiform discharges in the 1-hour EEG

Secondary

MeasureTime frame
Difference between the mesial and lateral temporal lobe epilepsy regarding effect of cathodal transcranial direct current stimulation

Countries

Egypt

Contacts

Public ContactEman El Zamarany

Lecturer of Clinical Neurophysiology Faculty of Medicine Cairo University

emanzamarany2@gmail.com+201063584548

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026