Effect Of Intravenous Metoprolol Tartrate On Mortality In Patients With Septic Shock Due To Ventilator-Associated Pneumonia

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

PACTR

Registry ID

PACTR202404531355476

Enrollment

100

Registered

2024-04-26

Start date

2023-10-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulatory System Respiratory

Interventions

intravenous metoprolol tartrate

routine management of septic shock according to surviving sepsis campaign without giving Metoprolol

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients (= 18 years old). Diagnosed with septic shock secondary to ventilator-associated pneumonia (VAP). Presenting with sinus tachycardia. Hemodynamically stabilized with mean arterial pressure (MAP) > 65 mmHg. Willingness to participate and provide informed consent.

Exclusion criteria

Exclusion criteria: Contraindications to beta-blockers. History of heart failure. Previous use of beta-blockers prior to septic shock. Development of complications from beta-blocker administration.

Design outcomes

Primary

Measure	Time frame
28-day mortality	—

Secondary

Measure	Time frame
Mechanical ventilation days;Days of ICU stay;Days of hospital saty	—

Countries

Egypt

Contacts

Public ContactHaytham Saber Meligy

Lecturer of Critical Care Medicine

Hmeligy1@gmail.com002035552030

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026