Effects of oral clonidine pre-medication on intra-operative blood loss during caesarean section under sub-arachnoid block

Effects of Oral Clonidine Pre-medication on Intra-Operative Blood Loss during Caesarean Section under Sub-Arachnoid Block in Federal Teaching Hospital Abakaliki

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

PACTR

Registry ID

PACTR202403873496250

Enrollment

160

Registered

2024-03-01

Start date

2018-03-26

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy and Childbirth

Interventions

Clonidine grouup

Placebo group

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Normotensive and mild to moderate hypertensive (controlled) pregnant women aged 18 to 45 years who were scheduled for elective caesarean section under SAB at the study centre Those who consented to participate in the study.

Exclusion criteria

Exclusion criteria: ? Patients below age 18 and above age 45years. ? Grandmultiparous women (parity greater or equal to 5). ? Patients with complications of pregnancy such as: placenta praevia, Abruptio placentae, pre-eclampsia with BP = 160/110mmHg, Eclampsia, pregnancy-induced hypertension or chronic hypertension in pregnancy with BP = 160/110mmHg. ? Emergency Caesarean sections ? Patients with Cardiovascular /Respiratory diseases ? Renal/hepatic disease patients ? Multiple gestations. ? Patients that took antihypertensive <24 hours before surgery. ? History of allergy to the study drug. ? Patients with height less or equal to 1.0m. ? Patients with previous caesarean section(s).

Design outcomes

Primary

Measure	Time frame
Volume of intra-operative blood loss	—

Secondary

Measure	Time frame
Haemodynamic stability of patients, neonatal APGAR Scores, incidence of side effects like nausea, vomiting, shivering, sedation, hypotension etc. and the need for rescue analgesia	—

Countries

Nigeria

Contacts

Public ContactJohn Okafor Egede

Consultant Department of Obstetrics and Gynaecology Alex Ekwueme Federal University teaching Hospital Abakaliki

egedejohno@gmail.com+2348037797950

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Sep 19, 2026