Anaesthesia
Conditions
Interventions
Nalbuphine patient controlled analgesia
Sponsors
Childrens Cancer Hospital Egypt 57357
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: both sexes aged 7-18 years admitted to the Children Cancer Hospital Egypt 57357 diagnosed with cancer and undergoing cancer therapy complicated by mucositis grade 3 and 4 (severe oral mucositis)
Exclusion criteria
Exclusion criteria: central nervous system disorders, delayed developmental milestones, or mental retardation that might interfere with the assessment of pain intensity known or suspected myopathy known or suspected allergy to any narcotic known history of intolerable side effects of opioids renal impairment (creatinine clearance less than 50 mL/min) hepatic dysfunction (liver enzymes elevated more than 10-fold) respiratory distress (SPO2 less than 92% on room air) cardiac disease (ejection fraction less than 40%) chronic pain complaints advanced or metastatic cancer scheduled for palliative care
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity using the Visual Analog Scale;Number of active and total pushes of PCA buttons;Total opioid consumption;Patient satisfaction using the Patient Satisfaction Score | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects e.g. sedation, respiratory depression, bradycardia, hypotension, nausea, vomiting, pruritus, and urine retention. | — |
Countries
Egypt
Contacts
Public ContactAhmed Ibrahim
Department of Anesthesia Intensive Care and Pain Management Faculty of Medicine Ain Shams University
Outcome results
None listed