Tuberculosis
Conditions
Interventions
Multimonth refill of antituberculosis drugs
Standard of care
Sponsors
University of California Berkeley
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Aim 1: 1) TB focal persons with =1 year of work experience; 2) Other stakeholders with =3 years of work experience in TB; 3) People with TB on treatment for =4 months including the respective treatment supporters. Aim 2: People with drug-susceptible PTB aged =15 years.
Exclusion criteria
Exclusion criteria: Aim 1 1) Unreachable participants Aim 2: 1) People with TB who are very ill and require close clinical and laboratory monitoring or hospitalization; 2) People with PTB likely to migrate to another district/ or place during the study period; 3) Treated with anti-TB drugs for =2 months; 4) People with drug-resistant TB; 5) People with extrapulmonary TB since treatment duration exceeds 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment success measured at 6 months following TB treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sputum smear conversion measured at 2 months following TB treatment initiation among people with bacteriologically confirmed pulmonary TB.;Sputum smear conversion measured at 6 months following TB treatment initiation among people with bacteriologically confirmed pulmonary TB.;Monthly anti-TB adherence rate calculated as the number of pills taken divided by the number expected to have been taken, expressed as a percentage. Adherence rates <85% will be considered poor, 85-94% as good, and =95% as excellent. | — |
Countries
Uganda
Contacts
Public ContactDamazo Kadengye
Research Scientist African Population and Health Research Center
Outcome results
None listed